Interaction Checker
Tuesday 31 March 2026
Three new comedications have been added in recent months and several prescribing resources have been updated to include new additions and revisions.
New comedications
Berberine (Vitamins/Supplements/Herbals)
Deutivacaftor/Tezacaftor/Vanzacaftor (Cystic Fibrosis Agents)
Vonoprazan (Gastrointestinal Agents)
Revised interaction classifications (colour changes)
The following interactions with encorafenib have been updated due to a new study showing encorafenib to be a strong inducer of CYP3A4:
↑ Green to Amber - Dexamethasone, hydrocortisone, methylprednisolone, ruxolitinib
↑ Amber to Red - Ensitrelvir, imatinib
Updated Prescribing Resources
Treatment Selector for Key COVID-19 Therapies
At-a-glance summary of interactions with COVID-19 antiviral therapies
At-a-glance summary of interactions with COVID-19 host-directed therapies