Interaction Checker

Website updates - February and March 2026

Tuesday 31 March 2026

Three new comedications have been added in recent months and several prescribing resources have been updated to include new additions and revisions.

New comedications
Berberine (Vitamins/Supplements/Herbals)
Deutivacaftor/Tezacaftor/Vanzacaftor (Cystic Fibrosis Agents)
Vonoprazan (Gastrointestinal Agents)

Revised interaction classifications (colour changes)
The following interactions with encorafenib have been updated due to a new study showing encorafenib to be a strong inducer of CYP3A4:
Green to Amber - Dexamethasone, hydrocortisone, methylprednisolone, ruxolitinib
Amber to Red - Ensitrelvir, imatinib

Updated Prescribing Resources
Treatment Selector for Key COVID-19 Therapies
At-a-glance summary of interactions with COVID-19 antiviral therapies
At-a-glance summary of interactions with COVID-19 host-directed therapies

Academic Supporters / Collaborators
Editorial Supporters / Research Funders